An LA detective is murdered because she has microfilm with the recipe to make cocaine cookies. A "Lethal Weapon" style cop team tries to find and stop the fiends before they can dope the nation by distributing their wares via the "Wilderness Girls" cookie drive.

A string of business robberies have taken place in the city's Wilson Heights neighborhood, all done by the same three crooks. Captain Thaddeus Harris is no longer in the same precinct with a certain group of cops that he doesn't like. That's why Harris is so happy to be in the Wilson Heights precinct. But then The Mayor tells Harris that business in the city is plummeting because of the robberies. Since there appears to be a leak in Harris's precinct, the Governor has sent in a team to stop the Wilson Heights gang. Much to Harris's dismay, the team is led by Commandant Eric Lassard, so Harris knows who the team members are -- exactly the cops that he doesn't like. The team members are Nick Lassard, Moses Hightower, Eugene Tackleberry, Larvell Jones, Debbie Callahan, Laverne Hooks, and Douglas Fackler. The stakes are raised when Commandant Lassard is accused of being the mastermind behind the robberies, and the team must clear his name.

Boy genius Michael Dean (Adkins) teams up with a super-talented chimpanzee and his caretaker (Modine) to take down an animal testing lab. In exchange the scientist gives the boy some pointers on the girl of his dreams.